Orally Disintegrating Tablets: Composition, Methods of Production, And Assessment

Abstract

Orally disintegrating tablets (ODTs) are a one of a kind dose structure meant to break down swiftly in the mouth without the requirement for water, giving a helpful option in contrast to individuals having trouble gulping customary pills. Metoclopramide hydrochloride oral disintegrating tablets (ODTs) were the focus of this research because of the potential they have to alleviate gulping issues. Using the right super disintegrant is the key to successful ODT definition using the direct pressure technique. Nine details were arranged using various super disintegrants, including sodium starch glycolate (SSG), croscarmellose sodium (CCS), and cross povidone (CP). Point of rest, compressibility record, Hausner's proportion, consistency of content, thickness, hardness, friability, drug content, wetting time, water retention proportion, scattering time, in-vitro crumbling time, and other pre- and post-pressure restrictions were considered when examining the definition.