Pharmacogenomics: Bridging the Gap between Pharmacology and Personalized Medicine

Authors

  • Abdullah Ibrahim Henishi, Salman Hutayl Alshammari, Ahmed Abdulaziz Samkri, Saud Ahmad Hassan Al Zahrani, Thamer Huthith Almutairi

Keywords:

Pharmacogenomics; Personalized medicine; Precision pharmacotherapy; Genetic polymorphism; Drug metabolism; Adverse drug reactions; Clinical implementation; Genomic medicine

Abstract

Pharmacogenomics is an emerging discipline that links pharmacology and personalized medicine by studying genetic variation in response to drugs. Genetic variations in genes encoding drug‐metabolizing enzymes, transporters, receptors, and immune‐related molecules are crucial for drug pharmacokinetics and pharmacodynamics, with resultant influence on therapeutic efficacy and the frequency of ADRs (Evans & Relling, 1999; Roden et al., 2019). However, failure to consider this genetic diversity in conventional "one-drug-fits-all" therapeutic regimens leads to ineffective patient treatment, drug toxicity and elevated healthcare cost (Wilke et al.,
2007).

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Published

2026-01-11

How to Cite

Abdullah Ibrahim Henishi, Salman Hutayl Alshammari, Ahmed Abdulaziz Samkri, Saud Ahmad Hassan Al Zahrani, Thamer Huthith Almutairi. (2026). Pharmacogenomics: Bridging the Gap between Pharmacology and Personalized Medicine. International Journal of Multidisciplinary Innovation and Research Methodology, ISSN: 2960-2068, 5(1), 7–12. Retrieved from https://ijmirm.com/index.php/ijmirm/article/view/228

Issue

Vol. 5 No. 1 (2026): (Jan-Mar 2026)

Section

Articles

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Copyright (c) 2026 International Journal of Multidisciplinary Innovation and Research Methodology, ISSN: 2960-2068

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.